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The electropsychophysiological biomarkers of depressive disorders

Not Applicable
Recruiting
Conditions
Mental and behavioral disorders
Registration Number
KCT0000702
Lead Sponsor
Chonnam National University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
155
Inclusion Criteria

1)Aged 19~55
2)Rt handedness, graduated from highschool
3)Diagnosed as major depressive disorder, depressive disorder NOS, dysthimic disorder by the DSM-IV criteria
4)HAMD-17>=14
5)With ability to complete various questionnaires
6)Can understand the objective of the study and sign informed consent

Exclusion Criteria

1)history of having neuroleptics(antipsychoticsm antidepresseant, anticonvulsant, anxiolytics, anticholinergics)
2)history of physical illness affecting cognitive function such as brain trauma, mental retardation, neurologic disorders like Parkinson's disease.
3)history of abuse/dependence of alcohol/other substance
4)history of disability of visual and auditory function
5)clinically significant impairement or unstable state of general medical condition( renal/hepatic/ cardiovascular/respiratory/neurovascular/endocrine/immune system)
6)Severe physical illnesses threatening life
7)other psychiatric disorder on DSM-IV Axis I: schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder NOS)
8)history of organic mental disorder, epilepsy or other convulsive disorder
9)history of prescribing anticonvulasant
10)patients needed hospitalization due to the psychoatric condition other than depression
11)history of ECT for current depressive episode
12)Pregnancy or breastfeeding

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hamilton depression rating scale
Secondary Outcome Measures
NameTimeMethod
Hamilton depression rating scale
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