To evaluate the efficacy of prapaundarikadi taila matrabasti and darvi taila matrabasti with dilatation by gradual anal dilator in moderate to severe sphincteric spasm in the management of parikartika w.s.r.to Fissure in ano.

Not yet recruiting

• Conditions: Anal fissure, unspecified,

• Registration Number: CTRI/2025/05/087335
• Lead Sponsor: Matoshri Asarabai Darade Ayurved College, Babhulgaon, Yeola

Brief Summary

Fissure in Ano is the disease which causes considerable discomfort and pain occure most commonly in the midline posterior of anal canal. In Ayurvedic literature "Parikartika" has been mentioned by Aacharya Sushrut a condition characterized by cutting and burning pain around the anus, penis, umbilics and neck of bladder cessation. Parikartika is occur by influence of vata and pitta dosha, vata causes pain like cutting with a sharp instrument i.e. Scissors and pitta causes burning sensation along with inflammation. When Vata is covered with faeces, the stool is constipated, patient suffers from severe pain and passes hard stools with difficulty and evacuation is delayed. Prapaundrikadi taila is explained by Acharya Charaka in Dwivraniya Chikitsa, based on the rasapanchaka madhura, kashaya and sheeta guna it does daha prashamana and vrana Ropana. Parikartika is Vranalakshanayukta gudavikara. Charaka mentioned Darvi taila as an Vranaropaka, Kandugna, and Vatanulomaka in nature . prapaundarikadi taila Matrabasti and Darvi taila matrabasti with dilatation by gradual  anal dilator by reducing pain, bleeding, inflammation, spasm and itching by keeping equilibrium of doshas and promoting wound healing .

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-14
• Study Start: 2025-05-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Patients of age group 18 years to 60 years were selected.
• Patients presenting with classical signs and symptoms like Pain, Burning Defecation, per rectal bleeding,itching,constipation ,Moderate to severe anal sphincteric spasm at anal region.
• Patients will be selected irrespective of gender, religion, socioeconomic status.

Exclusion Criteria

• 1.patients with disease like ,ulcerative colitis,crohns disease,syphilis.
• 2.patients with co-morbidities like Hypertention, diabetes mellitus,HIV,hepatitis.
• 3.Pregnant and lactating women .

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The parameters will be noted down before and after treatment. the patient will be diagnosed based on symptoms of parikartika Explained in Ayurvedic and modern texts.	0th,7th,14th,21st,28th,35th
1. Pain	0th,7th,14th,21st,28th,35th
2. Burning Defecation	0th,7th,14th,21st,28th,35th
3. Bleeding per anum	0th,7th,14th,21st,28th,35th
4. Itching	0th,7th,14th,21st,28th,35th
5. Sphincteric Spasm	0th,7th,14th,21st,28th,35th
6. Wound Healing	0th,7th,14th,21st,28th,35th
7. Tenderness	0th,7th,14th,21st,28th,35th

Trial Locations

Locations (1)

Matoshri Asarabai Darade Hospital Babhulgaon Yeola; 🇮🇳 Nashik, MAHARASHTRA, India

Matoshri Asarabai Darade Hospital Babhulgaon Yeola

🇮🇳Nashik, MAHARASHTRA, India

Dr Nitin Vishnudas Dudhate

Principal investigator

8788640192

nitindudhate98@gmail.com