跳至主要内容
临床试验/CTRI/2025/05/087335
CTRI/2025/05/087335尚未招募不适用

Comparative clinical trial to evaluate the efficacy of prapaundarikadi taila matrabasti and darvi taila matrabasti with dilatation by gradual anal dilator in moderate to severe sphincteric spasm in the management of parikartika w.s.r.to Fissure in ano.

Matoshri Asarabai Darade Ayurved College, Babhulgaon, Yeola1 个研究点 分布在 1 个国家目标入组 68 人开始时间: 2025年5月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
68
试验地点
1
主要终点
The parameters will be noted down before and after treatment. the patient will be diagnosed based on symptoms of parikartika Explained in Ayurvedic and modern texts.

研究概览

简要总结

Fissure in Ano is the disease which causes considerable discomfort and pain occure most commonly in the midline posterior of anal canal. In Ayurvedic literature "Parikartika" has been mentioned by Aacharya Sushrut a condition characterized by cutting and burning pain around the anus, penis, umbilics and neck of bladder cessation. Parikartika is occur by influence of vata and pitta dosha, vata causes pain like cutting with a sharp instrument i.e. Scissors and pitta causes burning sensation along with inflammation. When Vata is covered with faeces, the stool is constipated, patient suffers from severe pain and passes hard stools with difficulty and evacuation is delayed. Prapaundrikadi taila is explained by Acharya Charaka in Dwivraniya Chikitsa, based on the rasapanchaka madhura, kashaya and sheeta guna it does daha prashamana and vrana Ropana. Parikartika is Vranalakshanayukta gudavikara. Charaka mentioned Darvi taila as an Vranaropaka, Kandugna, and Vatanulomaka in nature . prapaundarikadi taila Matrabasti and Darvi taila matrabasti with dilatation by gradual  anal dilator by reducing pain, bleeding, inflammation, spasm and itching by keeping equilibrium of doshas and promoting wound healing .

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients of age group 18 years to 60 years were selected.
  • Patients presenting with classical signs and symptoms like Pain, Burning Defecation, per rectal bleeding,itching,constipation ,Moderate to severe anal sphincteric spasm at anal region.
  • Patients will be selected irrespective of gender, religion, socioeconomic status.

排除标准

  • 1.patients with disease like ,ulcerative colitis,crohns disease,syphilis.
  • 2.patients with co-morbidities like Hypertention, diabetes mellitus,HIV,hepatitis.
  • 3.Pregnant and lactating women .

结局指标

主要结局

The parameters will be noted down before and after treatment. the patient will be diagnosed based on symptoms of parikartika Explained in Ayurvedic and modern texts.

时间窗: 0th,7th,14th,21st,28th,35th

1. Pain

时间窗: 0th,7th,14th,21st,28th,35th

2. Burning Defecation

时间窗: 0th,7th,14th,21st,28th,35th

3. Bleeding per anum

时间窗: 0th,7th,14th,21st,28th,35th

4. Itching

时间窗: 0th,7th,14th,21st,28th,35th

5. Sphincteric Spasm

时间窗: 0th,7th,14th,21st,28th,35th

6. Wound Healing

时间窗: 0th,7th,14th,21st,28th,35th

7. Tenderness

时间窗: 0th,7th,14th,21st,28th,35th

次要结局

未报告次要终点

研究者

发起方
Matoshri Asarabai Darade Ayurved College, Babhulgaon, Yeola
申办方类型
Other [[self]]

研究点 (1)

Loading locations...

相似试验