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Clinical Trials/NCT03989921
NCT03989921
Completed
Not Applicable

Ovarian Reserve and Embryo Implantation

Centre Hospitalier Universitaire de Nīmes1 site in 1 country598 target enrollmentNovember 29, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ovarian Reserve
Sponsor
Centre Hospitalier Universitaire de Nīmes
Enrollment
598
Locations
1
Primary Endpoint
The embryo implantation rate at 5 weeks after transfer is defined by the presence of an embryo with objective cardiac activity by ultrasound
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Compare, in young patients with In vitro fertilization (IVF), the rate of embryo implantation by early culture transfer (J2-J3) between 2 groups of patients: "normo responders" vs. "poor responders".

Registry
clinicaltrials.gov
Start Date
November 29, 2018
End Date
April 30, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Centre Hospitalier Universitaire de Nīmes
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • IVF patient managed with or without ICSI between 01/01/2014 and 30/06/2015 in one of the two study centres
  • Age \< 35 years old
  • Fresh transfer of at least one embryo between D2 and D6
  • patients who have already received one or more transfer attempts.

Exclusion Criteria

  • No fresh transfer (Freeze All, segmentation failure, stimulation failure)
  • Double successive embryo transfer (e. g. J3-J5). We did not retain these cases because if only one of the 2 embryos is implanted, it is not possible to know which transfer it corresponds to.
  • Maternal serum FSH determination \< 4 IU/ml at D3 in the baseline balance sheet (hypogonadotropic hypogonadism)

Outcomes

Primary Outcomes

The embryo implantation rate at 5 weeks after transfer is defined by the presence of an embryo with objective cardiac activity by ultrasound

Time Frame: 5weeks

The embryo implantation rate corresponds to the number of embryos with cardiac activity found on the number of embryos transferred

Study Sites (1)

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