Effect of various tricaliumphosphat-based bone grafting materials on osteogenesis 6 months after sinus floor augmentation in humans- a prospetive clinical, radiological, immunohistochemical and histomorphimetric study utilizing hard tissue histology and a split mouth desig

Not Applicable

Recruiting

Conditions: atrophy of the partially edentulous alveolar ridge in the posterior maxilla after tooth loss
K08.2
Atrophy of edentulous alveolar ridge

Registration Number: DRKS00007538

Lead Sponsor: Stiftungsprofessur für Experimentelle Orofaziale MedizinPhilipps-Universität MarburgFachbereich Medizin (MZ ZMK)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 400

Inclusion Criteria

partial edentulism in the upper post-canine area,
residual height of alveolar crest of less than 3 mm, width of alveolar crest of more than 6 mm

Exclusion Criteria

compromised general health (ASA (III or IV) – American Society of Anaesthesiology) , periodontitis, pathologies of maxilary sinus and Schneiderian membrane, drug or alcohol addictions

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
High amount of newly formed bone in the augmented sinus floor in combination with high biodegradation of the synthetic bone grafting material and formation of functional bone tissue 6 months after sinus floor augmentation utilizing different tricalcium phosphate-based bone grafting materials as determined by evaluation of histological sections and x-rays as well as volume stability of the grafted area and its association with patent dependent parameters including BMI and smoking, age gender and hormonal factors after

Secondary Outcome Measures

Name	Time	Method
Volume stability of the grafted area and high survival rates of the dental implants as determined by clinical follow-up and evaluation of cone beam CTs utilizing spezialized software 2 and 5 years after implant placement.