Finding association between eye ultrasound parameter at admission to hospital in brain injury patients with clinical recovery

Not yet recruiting

Conditions: Concussion, (2) ICD-10 Condition: S061||Traumatic cerebral edema,

Registration Number: CTRI/2017/11/010350

Lead Sponsor: Department of anaesthesia and intensive care

Brief Summary: Neuro-monitoring using noninvasive techniques can have therapeutic and prognostic implications especially in isolated moderate to severe Traumatic Brain Injury (TBI) patients. To the best of our knowledge, no study till date has correlated ultrasonographically(USG) measured Optic Nerve Sheath Diameter (ONSD) with outcome in patients with isolated moderate to severe TBI. Hence, we hypothesize that Intracranial Pressure measured by noninvasive methods such as measurement of ONSD by USG and Pulsatality Index (PI) by Transcranail doppler ( TCD) at hospital admission (within 24 hours of injury) may correlate with early neurological outcome in patients with isolated moderate to severe TBI. We plan an observational study to find correlation of ultrasound measured ONSD at admission with early neurological outcome (at post-injury one month and three months) in patients with moderate to severe traumatic brain injury.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 150

Inclusion Criteria

1.Patients with Traumatic brain injury (TBI) 2.Age.
18-60 years 3.Isolated TBI 4.Patients admitting to Advanced Trauma Center, Postgraduate institute of medical education and research, Chandigarh within 24 hours of Head Injury.

Exclusion Criteria

1.Age <18 year or > 60 years 2.TBI with major orthopedic trauma 3.Orbital trauma and orbital nerve lesions 4.If neurosurgical intervention done prior to Advanced Trauma Center admission.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of ONSD measured by ultrasonography in moderate-severe isolated head injury patients at admission with neurological outcome assessed by GOS-E at 1 months and 3 months	1 month and 3 month

Secondary Outcome Measures

Name	Time	Method
Correlation of Marshall Score from CT Scan in moderate-severe isolated head injury patients at admission with neurological outcome assessed by GOS-E at 1 months and GOS-E at 3 months	1 month and 3 month
Correlation of Pulsatility index (PI) measured by TCD in moderate-severe isolated head injury patients at admission with neurological outcome assessed by GOS-E at 1 months and 3 months	1 month and 3 month

Trial Locations

Locations (1): Postgraduate institute of medical education and research, chandigarh
🇮🇳
Chandigarh, CHANDIGARH, India
Postgraduate institute of medical education and research, chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Gourav mittal
Principal investigator
9466203593
dr.gmittal@gmail.com