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Clinical Trials/ISRCTN17792989
ISRCTN17792989
Completed
N/A

A pragmatic, multi-centre, three-arm randomised controlled trial to assess the clinical effectiveness and safety of time lapse imaging in in-vitro fertilisation treatment

Queen Mary University of London0 sites1,575 target enrollmentApril 18, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
In vitro fertilization
Sponsor
Queen Mary University of London
Enrollment
1575
Status
Completed
Last Updated
last year

Overview

Brief Summary

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32611445/ protocol (added 05/07/2020) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39033010/ (added 22/07/2024)

Registry
who.int
Start Date
April 18, 2018
End Date
September 30, 2023
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • The inclusion criteria are broad in keeping with the latest NICE guidelines (2013\) for NHS funded IVF/ICSI treatment.
  • Participants undergoing IVF/ICSI treatment and:
  • 1\. The woman is between 18 and 42 years of age at the time of consent
  • 2\. The male partner is at least 18 years of age at the time of consent
  • 3\. Receiving the first, second or third IVF/ICSI treatment cycle
  • 4\. Both partners give written informed consent
  • 5\. Those having at least 3 2PN embryos (showing 2 pro\-nucleii which is a sign of normal fertilisation) on day of fertilization check

Exclusion Criteria

  • Current exclusion criteria as of 06/04/2020:
  • 1\. Participants concomitantly participating in other interventional trials
  • 2\. IVF/ICSI treatment using donor gametes
  • 3\. Planned pre\-implantation genetic diagnostics or screening (PGS/PGD)
  • Previous exclusion criteria:
  • 1\. Participants who have been randomised previously to this trial
  • 2\. Participants concomitantly participating in other trials
  • 3\. IVF/ICSI treatment using donor gametes
  • 4\. Planned pre\-implantation genetic diagnostics or screening (PGS/PGD)

Outcomes

Primary Outcomes

Not specified

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