Comparison of efficacy of adding Gabapentin, or Celecoxib or combination of them to analgesic method in knee and shoulder arthroscopy

Phase 2

Conditions: Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
Recurrent
Tear of meniscus
Condition 1: Meniscus Tear. Condition 2: Rotator cuff tear. Condition 3: Bankart lesion. Condition 4: Anterior cruciate ligament tear.
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
M24.4

Registration Number: IRCT201205217274N5

Lead Sponsor: Vice chancellor for research, Guilan University of Medical Science

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 104

Inclusion Criteria

age between 18 to 75 years old; Physical status according to ASA (grades:I,II, or III); VAS score more than 5; Operation time less than 1.5 hour; Oral and written consent form. Exclusion criteria: Any patients operated under local anesthesia; Hyper-sensitivity and/ or contra-indication to the drugs (Gabapentin or Celecoxib); History of coagulopathies or thromboembolic diseases; History of M.I, C.V.A, Epilepsy, Renal or hepatic dysfunction, Psychological disorders; Alcohol or drug abuse; usage of pain-killer drug up to 2 days before surgery; History of chronic pain and usually usage of pain-relief drugs.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total Pethedin usage. Timepoint: at 6 and 24 hour post surgery. Method of measurement: milligram.;Pain intensity. Timepoint: at 6 and 24 hour post surgery. Method of measurement: Visual analogue score.

Secondary Outcome Measures

Name	Time	Method
ausea/ vomiting. Timepoint: at 6 and 24 hour post surgery. Method of measurement: Classified as follow: 0 = not present, 1 = nausea, 2 = vomit and 3 = repeated vomit or need treatment.;Sedation score. Timepoint: at 6 and 24 hour post surgery. Method of measurement: 1 = completely awake, 2 = awake but drowsy, 3 = asleep but responsive to verbal commands, 4 = asleep but responsive to tactile stimulus and 5 = asleep and not responsive to any stimulus.;Dizziness. Timepoint: at 6 and 24 hour post surgery. Method of measurement: present/ not present.