Prospective Evaluation of Patient Preferences for Outcomes of Hormonal Agents and Chemotherapy in Combination With Androgen Deprivation Therapy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 1,020
- Locations
- 1
- Primary Endpoint
- Log-odds (preference weights) by participant cancer type and country
Study Overview
Brief Summary
The purpose of this study is to quantify and publish participants' relative preferences for outcomes of chemotherapy and novel oral hormonal agents when added to androgen deprivation therapy (ADT) for participants with locally-advanced and metastatic hormone-sensitive prostate cancer (mHSPC). This study will also quantify the importance of administration factors related to convenience relative to treatment outcomes.
Detailed Description
The study will develop and administer a discrete-choice experiment (DCE) to quantify tradeoff preferences of participants with mHSPC and locally-advanced prostate cancer in various countries. Data/surveys are being collected in: United States, Canada, UK, France, Spain, Japan, China and South Korea.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •For interviews (attribute prioritization and pretest interviews)
- •Diagnosis of mHSPC with or without previous experience with ADT
- •Able to read and understand the survey language
- •Able to provide informed consent For online survey
- •Diagnosis of mHSPC or locally-advanced prostate cancer with or without previous experience with ADT
- •Able to read and understand the survey language
- •Able to provide informed consent
Exclusion Criteria
- •Not applicable
Outcomes
Primary Outcomes
Log-odds (preference weights) by participant cancer type and country
Time Frame: 1 day (once through survey)
Log-odds indicate participants' relative preferences for treatments with each attribute level in the study, all else equal.
Secondary Outcomes
- Relative importance weights by participant type and country(1 day (once through survey))