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Local and Widespread Hypoalgesic Effects of Neurodynamic Mobilization in Healthy Controls

Not Applicable
Completed
Conditions
Pain
Pain, Neuropathic
Interventions
Other: Neurodynamic Tensioner Mobilization
Other: Sham Neurodynamic Mobilization
Other: Neurodynamic Slider Mobilization
Registration Number
NCT03674489
Lead Sponsor
Brenau University
Brief Summary

Background \& Significance Pain is the primary reason many patients seek care from healthcare professionals who utilize various manual therapy techniques. Gaining further understanding of the hypoalgesic properties of such techniques can enable practitioners to more skillfully integrate them in managing patients presenting with pain. Previous research has revealed that various manual techniques result in both local and widespread hypoalgesic changes in asymptomatic controls and patients in pain. Much of this previous research has investigated thrust manipulation; however, there is a paucity of similar research investigating these effects in neurodynamic mobilization.

Specific Aims Aim: To assess for immediate local and widespread hypoalgesic effects of neurodynamic mobilization applied to the upper extremity.

Hypotheses:

* Subjects who receive neurodynamic mobilizations will exhibit greater positive changes in local and widespread Qualitative Sensory Testing (QST) measures compared to those who receive a sham mobilization.

* Subjects who receive neurodynamic mobilizations will exhibit greater positive changes in elbow ROM and reported sensation intensity with upper limb neurodyndamic testing as compared to those who receive a sham mobilization.

Aim: To assess for differences in immediate local and widespread hypoalgesic effects of sliding vs tensioning neurodynamic mobilization techniques applied to the upper extremity

Hypotheses:

* Subjects who receive sliding neurodynamic mobilizations will exhibit greater positive changes in local and widespread QST measures compared to those who receive tensioning neurodynamic mobilization

* Subjects who receive sliding neurodynamic mobilizations will exhibit greater positive changes in elbow range of motion (ROM) and reported sensation intensity with upper limb neurodynamic testing testing compared to those who receive a tensioning neurodynamic mobilization

Detailed Description

See protocol uploaded in documents section

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Age: 18-65
  • Ability to speak and comprehend English.
Exclusion Criteria
  • Current neck or upper extremity symptoms
  • Disorders that could result in impaired sensation - such as diabetes.
  • Current use of prescription pain medication or other medications that could result in altered pain perception - such as anti-anxiety medications or anti-depressants.
  • History of any chronic painful condition
  • Diagnosis of any major psychiatric disorder
  • Current pregnancy
  • Any painful condition within the past 3 months for which care was sought

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Neurodynamic Tensioner MobilizationNeurodynamic Tensioner Mobilization-
Sham Neurodynamic MobilizationSham Neurodynamic Mobilization-
Neurodynamic Slider MobilizationNeurodynamic Slider Mobilization-
Primary Outcome Measures
NameTimeMethod
Pressure Pain Threshold (PPT)change from baseline immediately after intervention

PPT will be assessed bilaterally over the thenar eminences, over the dorsal aspect of the 1st carpometacarpal (CMC) joint, and over the tibialis anterior using a pressure algometer with an affixed 1cm2 rubber tip.

Thermal Pain Threshold (TPT)change from baseline immediately after intervention

TPT will be assessed bilaterally over the thenar eminences, over the dorsal aspect of the 1st carpometacarpal (CMC) joint, and over the tibialis anterior.

Thermal Pain Tolerance (TPTol)change from baseline immediately after intervention

TPTol will be assessed bilaterally over the thenar eminences, over the dorsal aspect of the 1st carpometacarpal (CMC) joint, and over the tibialis anterior.

Elbow Extension ROM Obtained on Neurodynamic Testingchange from baseline immediately after intervention

A neurodynamic test of the median nerve will be performed according to the ULNT1 procedure originally described by David Butler. Degrees of elbow extension will then be recorded using a universal goniometer, and each subject will rate each of the following 5 sensory descriptors on a 10 cm Visual Analog Scale (VAS): "Stinging", "Tingling", "Tightness", "Sharpness", and "Numbness". The average of the 5 sensory descriptor ratings will then be averaged to create a single sensory descriptor VAS score - as outlined in Beneciuk et al 2009.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Brenau University

🇺🇸

Gainesville, Georgia, United States

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