Effect of intravenous Aminophylline injection on preventing renal dysfunctio
Phase 3
- Conditions
- Recovery of moderate to severe asphyxia in newborns.Asphyxia and hypoxemia
- Registration Number
- IRCT20181201041815N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Neonate with Moderate and Severe Asphyxia
Exclusion Criteria
Congenital Anomalies
Prematurity(Gestational age=37 week)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The neonates’ fluid intake. Timepoint: Before and after the intervention 24 hours after intervention and during the 4th and 7th day of life. Method of measurement: Using Schwartz's formula, in two studied groups.;Urine volume in the first three days,. Timepoint: Before and after the intervention 24 hours after intervention and during the 4th and 7th day of life. Method of measurement: Using Schwartz's formula, in two studied groups.;Serum electrolytes including Sodium, Potassium, Calcium, serum Creatinine. Timepoint: Before and after the intervention 24 hours after intervention and during the 4th and 7th day of life. Method of measurement: Using Schwartz's formula, in two studied groups.;GFR. Timepoint: Before and after the intervention 24 hours after intervention and during the 4th and 7th day of life. Method of measurement: Using Schwartz's formula, in two studied groups.
- Secondary Outcome Measures
Name Time Method ung disease. Timepoint: During the 4th and 7th day of life. Method of measurement: Chest X ray.;Intra Ventricular Hemorrhages seizure. Timepoint: During the 4th and 7th day of life. Method of measurement: Brain sonography and nursing documentation related to seizure.;Death. Timepoint: During the 4th and 7th day of life. Method of measurement: Shift documentation.