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临床试验/NCT06410911
NCT06410911尚未招募不适用

Analgesic Effect of Subcostal Transversus Abdominis Plane Block Versus Erector Spinae Block in Patients Undergoing Open Cholecystectomy Surgery

Sohag University0 个研究点目标入组 100 人开始时间: 2024年6月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
Compare analgesic effect of both groups post open cholecystectomy surgery

研究概览

简要总结

Open cholecystectomy is a surgical procedure involving the removal of the gallbladder through a traditional, open abdominal incision the surgeon makes an incision in the upper abdomen, exposes the gallbladder, and carefully disconnects and removes it. Postoperative pain management is a critical aspect of patient care following cholecytectomy surgery. Inadequate pain control can lead to a cascade of complications, including atelectasis, pneumonia, and delayed mobilization. These complications can prolong hospital stays, increase healthcare costs, and lead to patient dissatisfaction. Regional anesthesia techniques, such as subcostal transversus abdominis plane (TAP) block abd erector spinae block are commonly used to provide effective analgesia after cholecystectomy surgery. These techniques target the nerves that supply the surgical site, providing pain relief without the need for opioids. Opioids are associated with a number of side effects, including nausea, vomiting, constipation, and respiratory depression. Subcostal TAP block is a relatively new technique that has been shown to be effective in providing postoperative analgesia after upper abdominal surgery. This technique involves injecting local anesthetic into the TAP, a fascial plane that lies between the internal oblique and transversus abdominis muscles. The TAP block provides anesthesia to the nerves that supply the abdominal wall, including the subcostal nerves. Erector Spinae Plane Block is a newer technique targeting the dorsal rami of the T7-T12 spinal nerves, potentially offering broader analgesia encompassing the abdominal wall, thorax, and diaphragm. Early studies suggest improved pain control and respiratory function compared to traditional methods.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 18 and 65 years
  • Both sex.
  • American Society of Anesthesiologists (ASA) I-II Undergoing elective open cholecystectomy surgery.
  • Patients who need at least 24hrs hospital admission.

排除标准

  • Known allergy to local anesthetics
  • Coagulopathy or bleeding disorders
  • Severe respiratory disease
  • Neurological disorders
  • Pregnancy

研究组 & 干预措施

Group A

Active Comparator

subcostal transversus abdominis plane block will be performed 50 patients undergoing open cholecystectomy surgery

干预措施: Subcostal Transversus Abdominis Plane block in patients undergoing open cholecystectomy surgery. (Procedure)

Group A

Active Comparator

subcostal transversus abdominis plane block will be performed 50 patients undergoing open cholecystectomy surgery

干预措施: Sbcostal transversus Abdominis block and erector spinae block for both groups (Drug)

Group B

Active Comparator

Ultrasound-guided Erector spinae block will be performed 50 patients undergoing open cholecystectomy surgery

干预措施: Erector Spinae Block in patients undergoing open cholecystectomy (Procedure)

Group B

Active Comparator

Ultrasound-guided Erector spinae block will be performed 50 patients undergoing open cholecystectomy surgery

干预措施: Sbcostal transversus Abdominis block and erector spinae block for both groups (Drug)

结局指标

主要结局

Compare analgesic effect of both groups post open cholecystectomy surgery

时间窗: 24 hours post operative

to Compare the analgesic efficacy of subcostal transversus abdominis plain block and Erector Spinae block using Visual Analoug Score in both rest and coughing

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mahmoud Abdellatif Mohamed

assistant lecturer of anaesthia an icu and pain managment

Sohag University

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