Evaluation of control of signs and symptoms of inflammation after third molar extractio

Not Applicable

• Conditions: Inflammation; pain; edema; trismus; C23.888.592.612; C23.888.277; C10.597.613.750.700; C23.550.470

• Registration Number: RBR-2x2ntz
• Lead Sponsor: niversidade Federal do Piauí

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-01-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

age between 18 and 35 years;
no systemic disease (ASA I);
not to use medications currently or in the previous week of the research;
To present the lower third molars in similar positions with similar patterns of root formation;
do not present allergy to the drugs used in the study;
To present surgical site without current signs and symptoms of infection

Exclusion Criteria

patients with a history of pregnancy or lactation; history of gastrointestinal bleeding or peptic ulcer;
allergy to aspirin or NSAIDS;
liver, kidney, haematological and central nervous system diseases;
continued use of psychoactive drugs, analgesics, steroidal and non-steroidal anti-inflammatory drugs and
smokers.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this study is to evaluate whether dexamethasone has a greater efficacy in the control of pain, edema and trismus in relation to etoricoxib after third molar extraction. Verified by visual analog scale in 7 days (pain), measurement of 5 facial measures in the preoperative and postoperative periods of 72h (edema) and measurement of inter-incisal distance in the preoperative and postoperative periods of 72h (trismus ).;It was observed that dexamethasone was more effective in controlling edema when compared to etoricoxib with p-value = 0.028.<br>There was no statistically significant difference for pain and trismus assessments.

Secondary Outcome Measures

Name	Time	Method
It is expected to evaluate whether dexamethasone is more effective than etoricoxib in controlling trismus after extractions of lower third molars;No difference was observed between dexamethasone and etoricoxib in the control of trismo after exodontia of lower third molars