Clinical relevance of circulating tumor cells, ctDNA and diagnostic leukapheresis in pancreatic ductal adenocarcinoma patients
Recruiting
- Conditions
- C25Malignant neoplasm of pancreas
- Registration Number
- DRKS00023362
- Lead Sponsor
- niversitätsklinikum Hamburg-Eppendorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
consent, PDAC, resectable
Exclusion Criteria
no consent, other than PDAC, not resectable
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The overall aim of the study is to establish liquid biopsy protocols for PDAC patients in order to enable a more detailed molecular characterization of the disease and performance of functional test such as drug testing on the cells in the future.
- Secondary Outcome Measures
Name Time Method KRAS Hot spot Mutation analysis, 24months follow up, WGS of single cells, cfDNA quantities, CTC counts, portal vein vs. peripheral vein