Relevance of circulating tumour cells in patients undergoing laparoscopic colon resection versus open resection: a randomised trial
Completed
- Conditions
- Colorectal cancerCancerMalignant neoplasm of the colorectal area
- Registration Number
- ISRCTN28212149
- Lead Sponsor
- Academic Medical Centre (AMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Aged between 40 and 80 years
2. Colorectal cancer including colon and rectosigmoid cancers
3. Informed consent
Exclusion Criteria
1. Prior midline laparotomy
2. American Society of Anaesthesiologists (ASA) grade III/IV
3. Laparoscopic surgeon not available
4. Prior upper and/or lower midline laparotomy
5. Emergency colectomy
6. Contraindications for epidural (coagulation disorders)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of circulating tumour material induced by the surgical procedure, measured before, during and after the surgical procedure.
- Secondary Outcome Measures
Name Time Method 1. The level of cytokines before, during and after the surgical procedure<br>2. Differences in genotype between primary tumour and circulating tumour cells