Streamlining lung cancer diagnosis through genomic testing of cytology smears

Not Applicable

Recruiting

• Conditions: ung cancer; Tumour genetics; Lung cancer; Cancer - Lung - Non small cell; Respiratory - Other respiratory disorders / diseases; Cancer - Lung - Small cell

• Registration Number: ACTRN12618001293257
• Lead Sponsor: Royal Brisbane and Womens Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-31
• Last Update Posted: 16 March 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

Patients with enlarged mediastinal and/ or hilar lymph nodes suggestive of lung cancer requiring EBUS TBNA for tissue diagnosis.

Exclusion Criteria

Patients deemed not suitable for bronchoscopy by their treating clinician
Patients deemed unfit for bronchoscopy on the basis of
•Severe respiratory insufficiency or hypoxia, moderate-to-severe hypoxemia or any degree of hypercarbia
•Continuous use of anticoagulants (eg, heparin, warfarin) ADP-Receptor inhibitors (Clopidogrel), GP-IIB/IIIA- inhibitors (Abciximac), fish oil, etc) which cannot be discontinued.
•Uncorrectable coagulopathy or bleeding diathesis
•Platelet dysfunction or platelet count <100×10
•History of major bleeding with bronchoscopy
•Partial tracheal obstruction or obstruction of the superior vena cava
Any other severe or life-threatening comorbidity that could increase the risk of bronchoscopic biopsy

Study & Design

• Study Type: Interventional
• Study Design: Not specified