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临床试验/NCT02554162
NCT02554162已完成不适用

Chewy Satiety - the Interplay Between Food Structure, Oral Processing and Satiety

VTT Technical Research Centre of Finland1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
1
主要终点
Postprandial satiety, assessed using 10 cm visual analogue scale (0=not at all, 10=Extremely)

研究概览

简要总结

This study examines if there are differences in satiety responses between structurally different wholegrain rye products.

详细描述

The study consists of a satiety trial and mastication trial. The satiety trial consists of five study visits. Five cereal products with berry soup are presented in random order for each subject serving one of them in each study visit (crossover study design). Each meal consists of rye product or wheat bread providing 190 kcal of energy and of 3 dl berry soup (3 dl) providing 140 kcal of energy. The participants are instructed to evaluate their satiety and related sensations before eating the test food, right after eating and then every 30 min until 210 min after breakfast consumption. The evaluated sensations are hunger, fullness, satiety, desire to eat and prospective food consumption ("How much would you be able to eat right now?"), "thirstiness", "mood", "vigourosness" and "pleasantness"."Pleasantness" will be evaluated only right after eating the test food.

Cereal food samples with 3-digit number codes will be offered to each participant in a random order in mastication trial. The study products are rye products with varying structures. First the participant is asked to evaluate the expected satiety of the product (How filling would you expect this portion to be on a scale from 0 (=not full at all) to 10 (=extremely full)). Secondly the same food will be served to the participant in three portions and the participant will be asked to masticate each portion until she considers it to be ready for swallowing. Instead of swallowing the bolus will be expectorated to a plastic container which is kept on ice. The mastication process is characterized by measuring electrical activity of facial muscles by electromyography (EMG). The mastication process will be video-recorded to support data handling.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • BMI 18.5-25 kg/m2
  • Habit of eating breakfast

排除标准

  • Significant changes in body weight (+ or - 4 kg) during the previous year
  • Pregnant or lactating
  • Missing teeth (except 3rd molars)
  • Acute temporomandibular disorders (TMD)
  • Dietary restrictions possibly affecting the study (celiac disease, allergies or aversions to cereal foods/high carbohydrate foods)
  • Abnormal eating behaviour (according to EDDS (Eating Disorder Diagnostic Scale))

结局指标

主要结局

Postprandial satiety, assessed using 10 cm visual analogue scale (0=not at all, 10=Extremely)

时间窗: In every 30 min until 210 min after consumption

次要结局

未报告次要终点

研究者

发起方
VTT Technical Research Centre of Finland
申办方类型
Other
责任方
Sponsor

研究点 (1)

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