CODP Imaging From a Dose Perspective
- Conditions
- Radiation
- Interventions
- Diagnostic Test: computed tomography
- Registration Number
- NCT03581110
- Lead Sponsor
- Universitätsmedizin Mannheim
- Brief Summary
The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT.
Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1957
- noncontrast-enhanced chest CT performed on one of the named devices
- imaging performed between August 2014 and September 2017
- CT protocol used as previously specified
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 2nd generation dual-source CT computed tomography 320 patients that have received a noncontrast-enhanced chest CT on our second generation dual-source CT scanner in inspiration only. 16-slice CT scanner computed tomography 1426 patients that have received a noncontrast-enhanced chest CT on our 16-slice clinical routine CT scanner in inspiration only. 3rd generation dual-source CT computed tomography 211 patients that have received a noncontrast-enhanced chest CT on our third generation dual-source CT scanner in inspiration and expiration.
- Primary Outcome Measures
Name Time Method organ specific radiation doses The organ dose calculations have been performed retrospectively. Therefore, the time frame is variable. The time set for the final outcome calculations was September 2017. Therefore, the time frame varies between 3 years and 1 week. Organ specific radiation doses of 17 individual organs
- Secondary Outcome Measures
Name Time Method