Assessment of Contrast Enhancement Boost for the Direct Identification of Pulmonary Emboli in Thoracic CT Angiography
- Conditions
- Pulmonary Embolism
- Interventions
- Diagnostic Test: Contrast Boost post processing technique
- Registration Number
- NCT04654156
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Pulmonary embolism is a common cardiovascular disease and thoracic CT angiography is currently considered the gold standard for its non-invasive diagnosis. However, the diagnostic performance of CT angiography can be hampered by an insufficient enhancement of pulmonary arteries. Contrast Enhancement Boost (CE Boost) is a post-processing technique using an iodine density map to artificially improve pulmonary artery enhancement.
This retrospective study compares standard CT-angiography images with CE Boost images to assess the potential improvement of diagnostic performance for the detection of pulmonary embolism.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Patient who underwent thoracic CT angiography for suspicion of pulmonary embolism in our institution between March and June 2018
- None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Pathological group Contrast Boost post processing technique Patients with pulmonary embolism on thoracic CT angiography Healthy group Contrast Boost post processing technique Patients without pulmonary embolism on thoracic CT angiography
- Primary Outcome Measures
Name Time Method Number of thrombi within each branch of the pulmonary arteries Between March and June 2018 The pulmonary arteries were divided into 11 zones according to their anatomical characteristics then each visible thrombus was reported in a Excel table according to the zone where it was located
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHRU Nancy
🇫🇷Nancy, Meurthe-et-Moselle, France