Comparison of blood levels and Sedation of Dexmedetomidine through mouth and nose in Childre
Not Applicable
Completed
- Conditions
- Health Condition 1: H00-H59- Diseases of the eye and adnexa
- Registration Number
- CTRI/2021/04/032511
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1) ASA Grade 1 and 2 Patients.
2)Weight 10 to 30 kg.
Exclusion Criteria
1)Parental refusal
2)ASA III, IV
3)OSA
4)Difficult airway
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the pharmacokinetics of 2 mcg/kg sublingual and intranasal dexmedetomidine in childrenTimepoint: Forty-five minutes before the induction of anaesthesia up to 120 minutes after surgery.
- Secondary Outcome Measures
Name Time Method 1)To evaluate the onset and duration of sedation with sublingual and intranasal Dexmedetomidine. <br/ ><br>2)To evaluate the quality of parental separation and the mask acceptance with sublingual and intranasal Dexmedetomidine <br/ ><br>3)To evaluate perioperative operative vitals (HR, SpO2, MAP) with sublingual and intranasal Dexmedetomidine <br/ ><br>4)To evaluate perioperative analgesia with sublingual ad intranasal Dexmedetomidine and post-operative recovery score with sublingual and intranasal DexmedetomidineTimepoint: Forty-five minutes before the induction of anaesthesia upto 120 minutes after surgery.