DEXMEDETOMIDINE ON POSTOPERATIVE NEUROMUSCULAR RECOVERY IN SPINAL SURGERY
Phase 3
- Conditions
- Health Condition 1: - Health Condition 2: M488- Other specified spondylopathiesHealth Condition 3: M489- Spondylopathy, unspecified
- Registration Number
- CTRI/2021/09/036221
- Lead Sponsor
- JAWAHARLAL NEHRU MEDICAL COLLEGE AND HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I & II patients of either sex.
Mallampatti grades I & II.
Patients planned for elective surgery.
Exclusion Criteria
Patients with cardiovascular disease like coronary artery disease, hypertension, etc.
Pulmonary disease like asthma, COPD, cor-pulmonale.
Patients with neuro-muscular, hepatic or major renal disease.
Patients with anticipated difficult intubation, potentially full stomach patients (trauma, morbid obesity, pregnancy) and diabetes mellitus.
History of alcohol or drug abuse.
History suggestive of hiatus hernia/GERD.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to achieve neuromuscular recovery, in term of TOFR â?¥ 70% and also â?¥90% after administration of reversal agent.Timepoint: 5 minute after administration of reversal agent <br/ ><br>15 minute after administration of reversal agent <br/ ><br>30 minute after administration of reversal agent <br/ ><br>60 minute after administration of reversal agent
- Secondary Outcome Measures
Name Time Method Time to achieve Modified Aldrete Score 9 or 10 <br/ ><br>To assess Ramsay Sedation Score <br/ ><br>To assess Patients Satisfaction Score <br/ ><br>Timepoint: 5 minute after administration of reversal agent <br/ ><br>15 minute after administration of reversal agent <br/ ><br>30 minute after administration of reversal agent <br/ ><br>60 minute after administration of reversal agent