Comparison of two methods of intravenous fluid administration in sick newborn babies with kidney failure.
Not Applicable
- Conditions
- Health Condition 1: N179- Acute kidney failure, unspecified
- Registration Number
- CTRI/2017/12/010761
- Lead Sponsor
- Jawaharlal Nehru Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Term and near term (34 weeks or more) sick neonates, birth weight 2000gm or more
2.AKI diagnosed using neonatal modification of KDIGO criteria
3.Non-oliguric i.e. urine output in previous 6 hours of at least 0.5 mL/kg/h
4.Anticipated to receive intravenous fluid for the next 48-72 hours
Exclusion Criteria
1)Major congenital anomalies, known renal anomalies or syndromic baby
2)Receiving drugs that affect fluid and electrolyte balance such as diuretics, mannitol, etc.
3)Refusal to give consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Net fluid balance <br/ ><br>2. Proportion of patients with fluid overloadTimepoint: 24, 48 and 72 hours
- Secondary Outcome Measures
Name Time Method Abnormal renal function at discharge <br/ ><br>Length of hospital stayTimepoint: At discharge;AKI stage <br/ ><br>Need for discontinuation of interventionTimepoint: upto 72 hours;Episodes of dyselectrolytemia <br/ ><br>Number of fluid bolusesTimepoint: 24 hourly;Percentage weight change <br/ ><br>Urine outputTimepoint: 12 hourly