The effectiveness of computerized cognitive training program for older adults with mild cognitive impairment and early dementia

Not Applicable

Completed

• Conditions: Mental and behavioural disorders

• Registration Number: KCT0009281
• Lead Sponsor: Gachon University Gil Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-12-23
• Last Update Posted: 2 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Subjects diagnosed with mild cognitive impairment according to Petersen’s criteria (Petersen et al., 1999) or early stage of major neurocognitive disorder according to DSM-5 (American Psychiatric Association, 2013)
2. Korean male or female over 60 years of age
3. Subjects with Clinical dementia rating global scale = 1
4. Subjects whose existing treatment (medication or face-to-face treatment) can be confirmed (existing treatment itself is irrelevant)
5. Subjects for whom no other structural causes of cognitive decline were found in brain MRI
6. After hearing and fully understanding the detailed explanation of this clinical trial, the subject voluntarily decided to participate and signed the consent form to comply with the precautions.

Exclusion Criteria

1. Subjects with mental illness other than mild cognitive impairment and early Alzheimer's disease (schizophrenia, bipolar disorder, depression, etc.)
2. Subjects diagnosed with or accompanied by cognitive decline due to other degenerative brain diseases, infections of the central nervous system (HIV, syphilis, etc.), head trauma, Creutzfeld-Jacob disease, Pick's disease, Huntington's disease, and Parkinson's disease
3. Subjects diagnosed with vascular dementia according to DSM-5 (American Psychiatric Association, 2013) criteria
4. Subjects with a history of stroke within 1 year of participating in the trial
5. Subjects who have participated in other treatment studies, including drugs, within 3 months before the start of the clinical trial (week 0)
6. Those who cannot undergo tests (e.g. fMRI) conducted during the clinical trial period
7. Cancer patients (systemic cancer including brain tumor)
8. Drug/alcohol abuser
9. Other subjects deemed unsuitable by researchers to participate in clinical trials

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MMSE;RCFT copy and recall test;Boston Naming test;Seoul Verbal Learning test;Word fluency test;Trail Making test;Stroop test

Secondary Outcome Measures

Name	Time	Method
apathy scale;Positive and negative affect scale;Geriatric depression scale;Quality of life scale;Mild behavioral impairment checklest and neuropsychiaric inventory;Usability scale