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Clinical Trials/ISRCTN55161632
ISRCTN55161632
Completed
Not Applicable

Detection of novel genetic polymorphisms (single nucleotide polymorphisms [SNPs]) within the aquaporins 1 and 5: an observational single-centre study

German Research Council (Deutsche Forschungsgemeinschaft [DFG]) (Germany)0 sites650 target enrollmentJuly 3, 2009
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ConditionsAquaporines, cell migration and inflammationRespiratoryAdult respiratory distress syndrome

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aquaporines, cell migration and inflammation
Sponsor
German Research Council (Deutsche Forschungsgemeinschaft [DFG]) (Germany)
Enrollment
650
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 3, 2009
End Date
TBD
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
German Research Council (Deutsche Forschungsgemeinschaft [DFG]) (Germany)

Eligibility Criteria

Inclusion Criteria

  • •1\. Acute respiratory distress syndrome:
  • •1\.1\. Timing: acute onset
  • •1\.2\. Oxygenation: partial pressure of oxygen in arterial blood (PaO2\)/fraction of inspired oxygen (FiO2\) ratio less than 200 mmHg (regardless of positive end expiratory pressure \[PEEP])
  • •1\.3\. Chest radiograph: bilateral infiltrates seen on frontal chest radiograph
  • •1\.4\. Pulmonary artery wedge (PAW): less than 18 mmHg when measured or no clinical evidence of left atrial hypertension
  • •2\. Lung function testing with body plethysmography\-revealed bronchial asthma
  • •3\. Patients with severe sepsis
  • •4\. Aged 18 to 70 years, both genders

Exclusion Criteria

  • •No written informed consent is obtained

Outcomes

Primary Outcomes

Not specified

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