Identification of genetic variations in patients with aortic type B dissectio
Recruiting
- Conditions
- I71.01
- Registration Number
- DRKS00015943
- Lead Sponsor
- Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
Included will be patients over 18 years that are reffered to the department of vascular and endovascular surgery (University Hospital Heidelberg). Aortic type B dissection will be diagnosed with Computer tomography angiography (CT-A) or magnetic resonance angiography (MR-A) independetly to the study protocol. Both complicated, uncomplicated acute and chronic type B dissections will be included into the study.
Patients give their written consent for genetic analysis and skin biopsy.
Exclusion Criteria
pregnant women, age < 18, traumatic aortic dissection, refusal of patient consent, local anesthetic intolerance (no skin biopsy!)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association of genetical findings with aortic dissection<br>Association of genetical findings with clinical Parameters (disease age of onset, clinical course, follow up)
- Secondary Outcome Measures
Name Time Method phenotypical findings (e.g. from skin biopsy)