The effect of progesterone in the prevention of preterm delivery

Phase 2

• Conditions: Preterm labour without delivery.; Preterm labour without delivery

• Registration Number: IRCT2016112331046N1
• Lead Sponsor: Vice-Chancellor for Research of Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

singleton pregnancies between 24-34 weeks gestational age; premature delivery confirmation by: regular uterine contractions (with a length of more the 30 second and more than 3 times per 10 minutes) with dilatation of the cervix 0-2 centimetres in nolipars and 0-3 centimetre in moltipars; intact fetal membranes.
exclusion criteria: rupture of the membranes during treatment; fetal anomaly; any evidence of fetal distress (chorioamnionitis, Preeclampsia, placental abruption, intrauterine growth restriction); sensitivity to progesterone (dizziness, headache, depression, high blood sugar during usage); history of medical illness in the mother (high blood pressure, cancer, epilepsy, chronic thromboambolic disease, liver disease); patients with asthma treated with oral beta-adrenergic.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delay of delivery. Timepoint: post partum. Method of measurement: documented data.

Secondary Outcome Measures

Name	Time	Method
eonatal distress. Timepoint: after delivery. Method of measurement: Documented data.;Birth weight. Timepoint: After delivery. Method of measurement: Documented data.;Apgar at birth. Timepoint: After delivery in 1 and 5 minutes. Method of measurement: Documented data.;Gestational age at birth. Timepoint: after delivery. Method of measurement: documented data.;Perinatal Mortality. Timepoint: after delivery. Method of measurement: documented data.;Fetal death. Timepoint: after delivery. Method of measurement: documented data.;NICU admission. Timepoint: after delivery. Method of measurement: documented data.