the influence of metformin and a low caloric diet on thyroid iodide uptake.
- Conditions
- physiological thyroid function in terms of thyroid iodide uptake and thyroid hormone productionknowledge can be extrapolated for treatment of thyroid diseases such as hyperthyroidism and thyroid carcinomaTherapeutic area: Body processes [G] - Physiological processes [G07]
- Registration Number
- EUCTR2016-001455-42-NL
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 17
. male
. No mental illness
. lnformed consent
. Healthy, specifically no history of thyroid disease or renal insufficiency
. Aged between 18-50 years
. Normalweight (BMl: 18.5-25.0 kg/m2)
. Maintained stable body weight for previous 6 months
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 17
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
. Any thyroid condition: hypo- or hyperthyroidism, thyroid cancer, other thyroid conditions.
. Any chronic illness, including diabetes mellitus, acute or chronic infections, other disease requiring treatment.
. Use of any medication or homeopathic medications. Use of paracetamol is allowed.
. Smoking
. Previous radioactive iodide scanning or other imaging techniques with administration of iodide containing contrast fluids within 6 months.
. Use of supplements that contain large quantities of iodide
. Structural alcohol intake > 3 glasses/day
. Subjects who have taken part in any drug trial within 3 months prior start of this study.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method