D-Dimer Vs Serial Compression Ultrasound Study

Phase 3

Completed

• Conditions: Deep Vein Thrombosis

• Registration Number: NCT00182351
• Lead Sponsor: Hamilton Health Sciences Corporation

Brief Summary

To determine whether d-dimer testing can be used to simplify and reduce the costs of the diagnostic approach to patients with clinically suspected deep vein thrombosis

Detailed Description

Not available

Study Timeline

• Study Start: 1996-04
• Study Completion: 1999-07
• Study First Submitted: 2005-09-13
• Study First Submitted QC: 2005-09-13
• Study First Posted: 2005-09-16
• Status Verified: 2006-09
• Last Update Submitted: 2006-09-07
• Last Update Posted: 2006-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 810

Inclusion Criteria

• first suspected deep vein thrombosis
• no previous venous thromboembolism
• referred to thromboembolism outpatient clinic

Exclusion Criteria

• comorbid condition limiting survival to less than six months
• contraindication to venography (contrast allergy, etc.)
• receiving long term warfarin therapy
• receiving full dose heparin therapy for more than 48 hours
• absence of symptoms during the five days immediately prior to presentation
• symptoms of pulmonary embolism
• pregnancy
• geographic inaccessibility which precludes follow-up

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
safety of withholding anticoagulants

Secondary Outcome Measures

Name	Time	Method
deep vein thrombosis
pulmonary embolism
death

Trial Locations

Locations (3)

Hamilton Health Sciences - Hamilton General Hospital; 🇨🇦 Hamilton, Ontario, Canada

St. Joseph's Hospital; 🇨🇦 Hamilton, Ontario, Canada

Hamilton Health Sciences - Henderson Hospital; 🇨🇦 Hamilton, Ontario, Canada