NCT01656499已完成2 期
Effect of AXOS on the Colon Metabolism in Healthy Volunteers
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- KU Leuven
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Fecal water toxicity
研究概览
简要总结
The purpose of this study is to evaluate the effect of AXOS on parameters of colon metabolism and gut health
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy volunteers
- •regular dietary pattern (3 meals/day)
- •age: 18-45y
- •BMI: 18,5-27 kg/m2
排除标准
- •intake of antibiotics 1 month prior to the study
- •abdominal surgery in the past, with the exception of appendectomy
- •intake of medication influencing the gastro-intestinal system 14 days prior to the study
- •in treatment at a dietician
- •serious liver- or kidney failure
- •vegetarians
- •intake of pre- and/or probiotics
- •Exposure to radioactivity 1 year prior to the study
结局指标
主要结局
Fecal water toxicity
时间窗: Participants are followed for 10 weeks, with measurements on 4 specific time points
次要结局
未报告次要终点
研究者
Kristin Verbeke
Professor Kristin Verbeke, Ph. D.
KU Leuven
研究点 (2)
Loading locations...
相似试验
已完成
4 期
Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy SubjectsHealthyNCT00853034KU Leuven20
已完成
不适用
AXOS and Microbial Metabolites in CKDChronic Kidney DiseaseNCT02141815Universitaire Ziekenhuizen KU Leuven40
进行中（未招募）
不适用
Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone FormersKidney StoneNCT04333745University of Alabama at Birmingham22
尚未招募
不适用
The effect of red meat consumption on human metabolic and gut health in free living adults.Metabolic HealthGut microbiome community profilingMetabolic and Endocrine - Normal metabolism and endocrine development and functionOral and Gastrointestinal - Normal oral and gastrointestinal development and functionACTRN12619000896178RMIT University24
已完成
不适用
Oxalobacter Formigenes Colonization and Urinary Oxalate ExcretionCalcium Oxalate UrolithiasisNCT03752684University of Alabama at Birmingham26