Comparing the effects of applying a multimodal analgesic strategy including cervical plexus block to improve postoperative pain management in patients undergoing carotid endarterectomy: a randomized, observer-blinded trial
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0008461
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
1. Adult patients undergoing elective carotid endarterectomy under general anesthesia (aged between 20 and 80 years of age)
2. American Society of Anesthesiologists (ASA) physical status classification (ASA class) I- III
3. A person who consented to the clinical trial and signed the subject consent form
1. Children under the age of 19, adults over the age of 80
2. Patients who refused cervical plexus block
3. Patients with neurological abnormalities
4. Patients with bleeding abnormalities or disabilities
5. Those who cannot undergo nerve block surgery due to recent systemic or partial infection
6. Patients who have taken opioids for a long time, patients with a history of severe side effects to opioids
7. Patients allergic to local anesthetics
8. A person who is judged to be inappropriate to participate in a clinical trial according to the judgment of the researcher
9. Patients with a history of previous CEA surgery
10. Patients who have failed cervical plexus block
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total Intravenous morphine equivalent for 24 hours after surgery
- Secondary Outcome Measures
Name Time Method Pain score in ICU at rest after surgery;Pain score when moving after surgery in the intensive care unit;Time of first narcotic analgesic administration after surgery;Frequency of hypertension (defined: systolic blood pressure >140 mmHg) 24 hours after surgery;Use of antihypertensive drugs (hydralazine) within 24 hours after surgery;Frequency of nausea or vomiting within 24 hours after surgery;Satisfaction with pain control after surgery;Sleep satisfaction on the first night after surgery;24-hour postoperative recovery questionnaire score;Frequency of postoperative complications (hoarseness, neurologic complication, recurrent laryngeal nerve block);cerebral hyperperfusion syndrome ;Intraoperative analgesia nociception index (ANI) score