A Randomized, Double-Blind, Multicenter Study Comparing the Glycemic Control Characteristics of Carvedilol and Metoprolol in Hypertensive Patients With Type II Diabetes Mellitus.

GlaxoSmithKline1 site in 1 country1,210 target enrollmentJune 2001

ConditionsHypertension

Drugscarvedilol metoprolol

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Hypertension
Sponsor: GlaxoSmithKline
Enrollment: 1210
Locations: 1
Primary Endpoint: Change from baseline in HbA1c at 5 months
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

To evaluate the effects of two different antihypertensive medications in the drug class of beta-blockers on control of glucose in Type II diabetic patients with high blood pressure.

Registry

clinicaltrials.gov

Start Date

June 2001

End Date

April 2004

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

GlaxoSmithKline

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Change from baseline in HbA1c at 5 months

Time Frame: 5 months

Secondary Outcomes

Blood pressure at 3 and 5 months. Body weight at 3 and 5 months. Lab values (glucose, insulin, triglycerides, cholesterol, and albumin:creatinine ratio) at 3 and 5 months.(5 months)