Evaluation the effect of Botulinium toxin injection on improving symptoms in patients with diabetic neuropathy
- Conditions
- Diabetic neuropathy.
- Registration Number
- IRCT20240116060710N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Definite diabetic neuropathy in the plantar area of ??both feet confirmed by NCV.
diabetes at least for three years
Consistency of the patient's medication for diabetic neuropathy for at least one month before entering the study
Filling out a personal consent form to enter the study
Having an underlying disease involving the peripheral nerves that causes symptoms similar to diabetic neuropathy in the plantar area.
Change in the patient's medication for diabetic neuropathy during at least one month before entering the study
History of myasthenia gravis
Allergy to botulinum toxin
kidney dysfunction
Having a history of alcohol consumption
Opioid addiction
Presence of pain with a typical dermatomal pattern caused by radiculopathy
Lack of patient consent to participate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain and quality of life and sleep quality of patients. Timepoint: at the begining of the study and in 1-4-8-12 week after intervention. Method of measurement: Evaluation of changes in scores of VAS, PSQI, SF-36 questionnaires.
- Secondary Outcome Measures
Name Time Method