The effect of botox in treatment of scar
Phase 3
- Conditions
- Keloid Lesion.Diseases of skin and soft tissue
- Registration Number
- IRCT2016020926489N1
- Lead Sponsor
- School of Medicine, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
patients with keloid lesion greater 2cm; patient age between 12-65 years of old; patients consent to participate in the study;
Exclusion criteria: patients with keloid lesion smaller than 1.9cm; lack of patient satisfaction in doing a research intervention; sensitivity to BTX-A; pregnant and breastfeeding women; patients with neuromuscular diseases.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pigmentation. Timepoint: 0-9monthes after last intervention. Method of measurement: By observers.;Vascularity. Timepoint: At beginig and 9th monthes after last injection. Method of measurement: By observers.;Height. Timepoint: At beginig and 9th monthes after last injection. Method of measurement: By observers.;Pliability. Timepoint: At beginig and 9th monthes after last injection. Method of measurement: By observers.
- Secondary Outcome Measures
Name Time Method Peri-lesional atrophy. Timepoint: At the begining of the study and 9 monthes after last injection. Method of measurement: assessment by ruler.