The effect of Botulinum toxin A injections for overactive bladder on detrusor contractility
Phase 4
- Conditions
- overactive bladderurine incontinence10046590
- Registration Number
- NL-OMON31265
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Male and female patients 20 - 70 years of age
Symptoms of overactive bladder for more than 6 months
Micturition frequency > 7 times/day
Incontinence episodes > 6/week
Capable of filling out a micturition diary
Exclusion Criteria
Treatment with Botulinum toxin A in the last 9 months
Treatment with anticholinergic drugs during the last 2 weeks
Active or repeated urinary tract infection
Peripheral neuropathy (i.e. Diabetic neuropathy)
Having an indwelling catheter
Malignancy in the area of the pelvis
Pelvic surgery less than 6 months ago
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoint is the change in detrusor contractility after Botulinum toxin<br /><br>A treatment.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary endpoint is the change in post void residual volume in relation<br /><br>to the detrusor contractility. </p><br>