Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

Phase 4

Completed

Conditions: Hospitalization
Infection

Interventions: Drug: Chlorhexidine gluconate (CHG)
Drug: Iodophor (10% povidone-iodine)

Registration Number: NCT03118232

Lead Sponsor: University of California, Irvine

Brief Summary: This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.

Detailed Description: Not available

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 13952

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Decolonization	Iodophor (10% povidone-iodine)	Nursing homes assigned to this arm will perform decolonization using topical antiseptic products.
Decolonization	Chlorhexidine gluconate (CHG)	Nursing homes assigned to this arm will perform decolonization using topical antiseptic products.

Primary Outcome Measures

Name	Time	Method
Hospital Transfers Due to Infection	18 months	Probability that a transfer to a hospital is due to an infection

Secondary Outcome Measures

Name	Time	Method
All Hospital Transfers	18 months	Probability that a discharge is to a hospital

Trial Locations

Locations (28): Buena Vista Care Center
🇺🇸
Anaheim, California, United States
Walnut Village Rehabilitation and Care Center
🇺🇸
Anaheim, California, United States
Gordon Lane Care Center
🇺🇸
Fullerton, California, United States
Windsor Gardens Care Center of Fullerton
🇺🇸
Fullerton, California, United States
Terrace View Care Center
🇺🇸
Fullerton, California, United States
Heritage Rehabilitation Center
🇺🇸
Torrance, California, United States
Sunnyside Nursing Center
🇺🇸
Torrance, California, United States
Del Amo Gardens Care Center
🇺🇸
Torrance, California, United States
Pacific Villa Inc.
🇺🇸
Long Beach, California, United States
Anaheim Crest Nursing Center
🇺🇸
Anaheim, California, United States
Bel Tooren Villa Convalescent Hospital
🇺🇸
Bellflower, California, United States
Capistrano Beach Care Center
🇺🇸
Capistrano Beach, California, United States
Sun Mar Nursing Center
🇺🇸
Anaheim, California, United States
Downey Care Center
🇺🇸
Downey, California, United States
West Anaheim Extended Care
🇺🇸
Anaheim, California, United States
Las Flores Convalescent Hospital
🇺🇸
Gardena, California, United States
Pacific Haven Subacute Healthcare Center
🇺🇸
Garden Grove, California, United States
Park Regency Care Center
🇺🇸
La Habra, California, United States
Regency Oaks Post Acute Care Center
🇺🇸
Long Beach, California, United States
Bixby Knolls Healthcare Center
🇺🇸
Long Beach, California, United States
Intercommunity Care Center
🇺🇸
Long Beach, California, United States
Royal Oaks Care Center
🇺🇸
Lynwood, California, United States
Norwalk Skilled Nursing and Wellness Center
🇺🇸
Norwalk, California, United States
Harbor Post-Acute Care Center
🇺🇸
Torrance, California, United States
Villa Elena Care Center
🇺🇸
Norwalk, California, United States
Torrance Care Center West
🇺🇸
Torrance, California, United States
Windsor Convalescent of North Long Beach
🇺🇸
Long Beach, California, United States
Vista Cove Care Center at Long Beach
🇺🇸
Long Beach, California, United States