Preoperative staging by combidex MRI in patients with resectable esophageal carcinoma
Completed
- Conditions
- esophageal cancer
- Registration Number
- NL-OMON28048
- Lead Sponsor
- Radboudumc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
•Patients with recently biopsy proven esophageal cancer, who are planned to undergo a esophagectomy with nCRT
•Patients with suspected lymph nodes metastases on EUS or CT before nCRT
Exclusion Criteria
•Unable to provide informed consent
•Known pregnancy or breastfeeding
Study & Design
- Study Type
- Not specified
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the feasibility and diagnostic accuracy of nano-MRI in detecting locoregional lymph node metastases in patients with esophageal cancer whom underwent nCRT
- Secondary Outcome Measures
Name Time Method -Diagnostic accuracy of the nano-MRI under anesthesia and controlled mechanical ventilation motion in detecting locoregional lymph node metastases in patients with esophageal cancer whom underwent nCRT <br /><br>-Diagnostic accuracy of the nano-MRI in detecting locoregional lymph node metastases ex-vivo after nCRT <br /><br>-Identify the effect of nCRT on the detection of lymph nodes metastases with nano-MRI<br /><br>-Identify the quantitative effect of anesthesia and controlled mechanical ventilation motion MRI compared with ‘breathhold’ MRI. <br /><br>-Compare the diagnostic accuracy of nano-MRI in detecting lymph node metastases with clinical staging results of esophageal cancer (CT, PET, EUS)