Clinical research on the efficacy of CNU in dissolving gallstones and improving gallstone-related symptom.
Not Applicable
Recruiting
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0000996
- Lead Sponsor
- Korea University Anam Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 220
Inclusion Criteria
1. Sonographically defined GB stone(diameter<15mm)
2. Stones are radiolucent on Plain X-ray.
3. GB EF = 50% in DICIDA biliary scan
Exclusion Criteria
1. patients with complicated GB stone such as acute cholecystitis.
2. high degree obese person (BMI>35kg/m2)
3. obstructive jaundice or CBD stone
4. liver disease(Abnormal LFT ( ALT >2x N)), liver cirrhosis
5. renal insufficiency
6. hyperesensitivity to bile acid
7. pregnancy or breast feeding women
8. malignancy
9. Patents with GI operation Hx
10. GB ejection fraction <50% or nonvisualization of GB
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Absence of GB stone in sonography;The change of diameter of largest GB stone in sonography
- Secondary Outcome Measures
Name Time Method Measurement of VAS related with GB stone related symptom according to treatment;adverse effect of CNU treatment