Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma

Recruiting

• Conditions: Melanoma

• Registration Number: NCT06861023
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Melanomas of the nail bed are often diagnosed at the locally advanced stage. The standard treatment was amputation of the finger or toe, but it has now been established that enlarged excision of the nail plate is sufficient under certain conditions. Reconstruction of the nail system can be performed by several techniques. Here, the investigators present a series of patients reconstructed by INTEGRA (dermal matrix) and skin graft

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-15
• Status Verified: 2025-02
• Study First Submitted: 2025-02-25
• Primary Completion: 2025-02-28
• Study First Submitted QC: 2025-02-28
• Last Update Submitted: 2025-02-28
• Study First Posted: 2025-03-06
• Last Update Posted: 2025-03-06
• Study Completion: 2025-03-25

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Patients who have undergone enlarged resection of the nail apparatus with immediate or delayed reconstruction in the setting of acral melanoma of the fingers or toes.

Exclusion Criteria

• Patients who have amputation, opposition of the pateint to the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional and cosmetic patient satisfaction	3 months minimum postoperative	Scores AOFAS (feet)(score ranging from 0, maximum disability, to 90, no disability), Scores QUICK DASH(score ranging from 0, no disability, to 100, maximum disability) and Mayowrist score (hands)(score ranging from 0, maximum disability, to 100, no disability)

Secondary Outcome Measures

Name	Time	Method
Post-operative complications	3 months minimum postoperative	Presence or absence of Postoperative complications (inclusion cyst, nail spicule, need for repeat surgery).
Recurrence of the disease	3 months minimum postoperative	Recurrence of the disease.

Trial Locations

Locations (1)

CHU NICE; 🇫🇷 Nice, Alpes Maritimes, France