A study to compare the preference of two contrasting paracetamol formulations in the management of osteoarthritis pai
Phase 4
Completed
- Conditions
- Osteoarthritis of the kneeMusculoskeletal - Osteoarthritis
- Registration Number
- ACTRN12607000565448
- Lead Sponsor
- GlaxoSmithKline Consumer Healthcare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
At least 45 years of age, good general health, diagnosis of osteoarthritis of the knee with the pain worse in one knee, pain must be suitable for treatment with a simple analgesic
Exclusion Criteria
History of a secondard cause of osteoarthritis, medical condition that may affect the ability to rate pain, any contraindication to the use of paracetamol or ibuprofen, intra-articular steroid injection to the knees within the last 2 weeks
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient preference for a particular treatment in the management of osteoarthritis pain[When patients have completed both 2 week arms of the study.]
- Secondary Outcome Measures
Name Time Method Patient satisfaction with treatment using a verbal rating scale.[Completed at the end of each 2 week treatment period.];Patient attitude towards treatment convenience[At the end of the study];Global assessment of response to treatment[At the end of each 2 week treatment period];Overall experience of pain using a verbal rating scale.[At the end of each 2 week treatment period];Quality of sleep during the night[At the end of each 2 week treatment period];Night time disturbance due to knee pain[At the end of each 2 week treatment period];Pain on waking[At the end of each 2 week treatment period];Pain on walking[At the end of each 2 week treatment period];Pain at rest[At the end of each 2 week treatment period];Compliance with medication[At the end of each 2 week treatment period]