Feasibility and Prognosis of Early Rehabilitation in Patients With Extracorporeal Membrane Oxygenation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Extracorporeal Membrane Oxygenation
- Sponsor
- JinyanXing
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- muscle ultrasound
- Last Updated
- 4 years ago
Overview
Brief Summary
ECMO is increasingly used in critically ill patients with severe circulatory and/or respiratory failure. Because of the catheterization of the femoral artery and femoral vein, usage of sedatives, and occasionally with neuromuscular blockers, ECMO patients are generally considered unsuitable for early activity. However, some recent retrospective studies and a small number of single-center, small-scale prospective studies have shown that early activity of ECMO patients is feasible, and early active activity is associated with recovery of independent function and reduction of delirium incidence.
Investigators
JinyanXing
Director
The Affiliated Hospital of Qingdao University
Eligibility Criteria
Inclusion Criteria
- •ECMO time ≥1 day
- •Aged older than16 years old and less than 70 years old
Exclusion Criteria
- •coma deep
- •sedation muscle relaxation (RAAS-3-5)
- •Active bleeding deep vein thrombosis
- •High dose of vasoactive drugs
- •unstable vital signs
- •Acute stage of myocardial infarction (within 2d)
- •Malignant arrhythmia
- •pregnancy
Outcomes
Primary Outcomes
muscle ultrasound
Time Frame: 7 days
The thickness of intercostal muscle and rectus femoris muscle was measured by ultrasound
Secondary Outcomes
- ECMO duration time(30 days)