Feasibility and Prognosis of Early Rehabilitation in Patients With Extracorporeal Membrane Oxygenation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- muscle ultrasound
研究概览
简要总结
ECMO is increasingly used in critically ill patients with severe circulatory and/or respiratory failure. Because of the catheterization of the femoral artery and femoral vein, usage of sedatives, and occasionally with neuromuscular blockers, ECMO patients are generally considered unsuitable for early activity. However, some recent retrospective studies and a small number of single-center, small-scale prospective studies have shown that early activity of ECMO patients is feasible, and early active activity is associated with recovery of independent function and reduction of delirium incidence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ECMO time ≥1 day
- •Aged older than16 years old and less than 70 years old
排除标准
- •coma deep
- •sedation muscle relaxation (RAAS-3-5)
- •Active bleeding deep vein thrombosis
- •High dose of vasoactive drugs
- •unstable vital signs
- •Acute stage of myocardial infarction (within 2d)
- •Malignant arrhythmia
- •pregnancy
结局指标
主要结局
muscle ultrasound
时间窗: 7 days
The thickness of intercostal muscle and rectus femoris muscle was measured by ultrasound
次要结局
- ECMO duration time(30 days)
研究者
JinyanXing
Director
The Affiliated Hospital of Qingdao University