Refractory In and Out of Hospital Cardiac Arrest Treated With Extracorporeal Membrane Oxygenation. Observational, Single Centre, Prospective Study.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiac Arrest
- Sponsor
- University of Milano Bicocca
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- 28 days survival
- Last Updated
- 14 years ago
Overview
Brief Summary
Extracorporeal membrane oxygenation (ECMO) support has been suggested to improve the survival rate in patients with refractory cardiac arrest (CA). Recent studies have also highlighted the potential early application of this method in improving the prognosis of prolonged cardiac arrest both for in hospital CA (INHCA) and out of hospital CA (OHCA). The rationale for use of ECMO in these patients is to optimize early perfusion of vital organs, curing the cause of CA and waiting for the recovery of the injured myocardium. The investigators have created a flow-chart to decide which patients are eligible. The aims of this study are to evaluate if, with this flow-chart, the investigators are able to detect which patients have more probability of survival.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adults 18-75 years old
- •In and out of hospital Witnessed Cardiac Arrest
- •No-flow time \< 5 min. or VF,VT,TP as rhythm of presentation
- •Low-flow time \< 45 min.
- •End Tidal CO2 \> 10 after 20 min.of CPR
Exclusion Criteria
- •Comorbidities such:
- •Terminal Malignancy
- •Aortic Dissection
- •Severe Cardiac Failure without transplant indication
- •Severe Aortic Valve Failure
- •Known Severe Peripheral arteriopathy
Outcomes
Primary Outcomes
28 days survival
Time Frame: 28 days
Secondary Outcomes
- Neurologic recovery(28 days)
- Cardiac recovery(28 days)
- Six months survival with minimal neurologic impairment(180 days)