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临床试验/NCT05195697
NCT05195697招募中不适用

ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care

Region Skane2 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
Region Skane
入组人数
3,000
试验地点
2
主要终点
Mortality

研究概览

简要总结

Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.

详细描述

At Skåne University Hospital approximately 6000 individuals are treated for acute abdominal diseases each year. Given the high number of patients, there is an urgent need to optimize acute surgical care. Lower complication rates would decrease hospital stay, health care costs as well as personal suffering.

Assessment instruments for risks and frailty are not validated for the acute setting and the investigators hypothesize there is room for improvement in prophylactic interventions and risk assessment. The investigators will study cohorts of patients with three different surgical diagnosis: acute pancreatitis, gastrointestinal bleeding and perforated ulcer aiming to identify risk factors for complications or death and to investigate assessment tools in this population. Using propensity score analysis, the investigators will try to identify treatment options associated with better outcome for subcohorts defined by frailty, comorbidity, age or gender. Specific factors of interest include: time to- and kind of treatment, handling of ongoing pharmacological therapy (anticoagulants, corticosteroids) and need for further treatments on a long time basis. The results from this project will be used in a future prospective study where prophylactic treatments and specific treatment options are studied.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients admitted to Skåne University hospital in need of acute surgical care -

排除标准

  • Below 18 years old

结局指标

主要结局

Mortality

时间窗: 5 years

Defined by Swedish registers

Reintervention

时间窗: 5 years

Defined by medical records

Recurrent disease

时间窗: 5 years

Defined by medical records

次要结局

  • Lengths of hospital stay(5 years)
  • complications(5 years)
  • Number of interventions(5 years)

研究者

发起方
Region Skane
申办方类型
Other
责任方
Sponsor

研究点 (2)

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