Risk Factors And Outcomes Of Hospital Acquired Acute Kidney Injury: A Tertiary Health Care Center Experience
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- AKI - Acute Kidney Injury
- Sponsor
- Alexandria University
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Recovery of kidney functions
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The aim of the study is to assess the common risk factors for development of hospital acquired acute kidney injury among hospitalized patients in Alexandria Main University hospital and their outcomes.
Detailed Description
Hospital-acquired AKI (HAAKI) is defined as acute renal insult occurring 48 hours or more after admission to a health care facility and It is estimated to occur in 13-18% of hospitalized patients. The early diagnosis of HAAKI reflects on improvement in morbidity and mortality rates especially in developing countries which goes parallel with the goal The International Society of Nephrology (ISN) to eliminate preventable or treatable deaths from AKI by 2025, the "0 by 25" initiative. Data concerning the spectrum of acute kidney injury (AKI) in Egypt are generally scarce.
Investigators
Mohamed Mamdouh Mahmoud Mohamed Elsayed , MD
Lecturer
Alexandria University
Eligibility Criteria
Inclusion Criteria
- •Fulfilment of definition of acute kidney injury according to KDIGO reference.
- •Age more than 18 years.
Exclusion Criteria
- •Mentally or physically unfit patients.
- •Patients who developed acute kidney injury within 48 hours of admission to hospital.
Outcomes
Primary Outcomes
Recovery of kidney functions
Time Frame: 12 weeks
(improvement of eGFR, serum creatinine to normal or previous baseline).
Secondary Outcomes
- Need for renal replacement therapy(12 weeks)
- mortality(12 weeks)
- progression to chronic kidney disease.(12 weeks)