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临床试验/NCT02949635
NCT02949635已完成不适用

Risks of Death, Hospital Readmission, and Institutionalization After Hospitalization in Acute Geriatric Unit

University Hospital, Lille7 个研究点 分布在 1 个国家目标入组 3,532 人开始时间: 2016年9月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
3,532
试验地点
7
主要终点
Number of death after discharge

研究概览

简要总结

Three events can be considered of major importance for patients after a hospitalization in an AGU: death, hospital readmission, and institutionalization. Current published data do not allow the clinician to simultaneously estimate the risk of hospital readmission, institutionalization and death of an older patient according to his/her characteristics and various complications that occurred during the hospitalization. However, clinicians often need to estimate these risks at hospital discharge to adapt their therapeutic choices, their proposals post-hospital care, and provide reliable and fair information to the patient and his relatives.

Estimating simultaneously the hazard for each of these three events can be complex. Indeed, a death event hinder the observation of re-hospitalization or institutionalization if death occurs before these events. The death should be considered a competing risk in these analyzes. Hospital readmission may modify the risk of death or institutionalization and should be considered as an intermediate factor for these event. This complexity cannot be accounted with classical statistical models, like logistic regression models.

The purpose of this study is to use more appropriate statistical models (multi-state models) to better estimate simultaneously the risks of hospital readmission, institutionalization, and death of a patient given after hospitalization in AGU, and to show that accuracy of these estimations can be improved by taking into account complications that occurred during the stay in AGU.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
75 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 75 years and over
  • Hospitalized in Acute Geriatric Unit
  • Covered by a health insurance

排除标准

  • Refusal to participate to the study, as expressed by the patient or his/her next of kin

结局指标

主要结局

Number of death after discharge

时间窗: 3 months

次要结局

  • Number of death after discharge(12 months)
  • Number of rehospitalization after discharge(at 3 and 12 months)
  • Number of institutionalization (NH admissions)(at 12 months)
  • Number of nosocomial infectious diseases during the index hospitalization(60 days)
  • Duration of clostridium difficile infection(60 days)
  • Length of stay of the index hospitalization(60 days)

研究者

发起方
University Hospital, Lille
申办方类型
Other
责任方
Sponsor

研究点 (7)

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