Mortality and Risk Factors in Patients With Acute Cardiogenic Pulmonary Edema: a Multicentric, Observational, Prospective Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Pulmonary Edema
- Sponsor
- University of Milan
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- mortality
- Last Updated
- 15 years ago
Overview
Brief Summary
The purpose of this study is to define the current treatment of patients ospitalized with acute cardiogenic pulmonary edema. Clinical and laboratory data collected in the Emergency Department will used to investigate the primary outcome (mortality) and risk factors related to the primary outcome.
Detailed Description
ACPE is a common cause of presentation to the Emergency Department (ED). Early recognition of high-risk patients could help in better locating human and technical resources and in deciding adequate treatment and site of care. The investigators planned a real life, multicentric, prospective, web-based observational study performed in Italian Emergency Departments. The investigators enroll consecutive patients admitted to the Emergency Department with acute cardiogenic pulmonary edema, that is defined as all the following: respiratory distress, bilateral rales and congestion on chest X-ray. Demographic, clinical and laboratory findings are collected on admission and during hospitalization to evaluate mortality and risk factors related to mortality.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all of the following:
- •acute-onset dyspnea
- •widespread pulmonary rales
- •pulmonary congestion on chest X- ray plus one of the following:
- •respiratory distress
- •respiratory rate ≥ 30
- •emogasanalysis: pH \< 7.35 and pCO2 \> 45 mmHg in Venturi-Mask 50%
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
mortality
Time Frame: Discharge from hospital