COVADIS study
Not Applicable
- Conditions
- COVID-19
- Registration Number
- PACTR202010472402152
- Lead Sponsor
- Medical Research Council Unit The Gambia at LSHTM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 1100
Inclusion Criteria
Adults and children of both genders without age limit being either suspect of COVID-19, or contacts of a confirmed COVID-19 patient following the WHO case definitions below, are eligible to participate in the study
Exclusion Criteria
- The subject (or parents/guardians for minors<18y) has not provided individual informed consent for the study; - The patient has already been sampled and is waiting for the results;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To validate a commercially available antigen-based rapid diagnostic test in suspected COVID-19 patients; 2. To develop a validated serology platform for determining serostatus and monitoring immune responses to SARS-CoV-2 infection; 3. To characterize the viral load and antibody dynamics in a cohort of confirmed COVID-19 patients; 4. To characterize at household level the sero-epidemiology of COVID-19 infections; 5. To determine the performance of saliva for the detection of SARS-CoV-2 RNA and antibodies in COVID-19 patients; 6. To determine the duration and infectivity of viral shedding in COVID-19 patients;
- Secondary Outcome Measures
Name Time Method To contribute to the COVID-19 response in WA by improving local diagnostic and surveillance capabilities.