NCT01155648已完成不适用
Increasing Pressure Support During Chest Wall Compression is Useful During Respiratory Therapy?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 2
- 主要终点
- Variation of mucus secretion aspirated.
研究概览
简要总结
The purpose of this study is to compare two physiotherapy techniques: chest wall compression versus chest wall compression plus increase of 10 cmH2O in inspiratory pressure.
详细描述
- After being placed in the supine position in bed, with head angle elevation at 30°, patients were randomized to:group 1 (G1): chest wall compression for ten minutes in chest or group 2 (G2): chest wall compression plus increase of 10 cmH2O in IP in PSV for ten minutes in chest.
- Clinical variables and APACHE II were registered.
- Parameters analyzed at the beginning (1) and at the end (2) of the protocol were: variation of peak pressure (ΔPp=Pp2-Pp1),variation of tidal volume (ΔVT =VT2-VT1), variation of dynamic compliance (ΔCdyn= Cdyn2-Cdyn1).
- The amount of variation of mucus secretion aspirated (ΔSa= Sa2-Sa1) at the end was also measured
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients on mechanical ventilation over 48 hours
- •With ventilatory drive
- •Hemodynamically stable MAP> 60 mmHg
- •With treatment of respiratory therapy
排除标准
- •Contra indication of increased positive inspiratory pressure
- •Peak pressure in the upper airway > 40 cmH2O
- •Osteoporosis diagnosis
- •Deny to participate in the study
结局指标
主要结局
Variation of mucus secretion aspirated.
时间窗: Two years
次要结局
- Hemodynamic and pulmonary parameters.(Two years)
研究者
研究点 (2)
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