The effect of three different volumes of 0.5% bupivacaine on the perfusion index ratio during the ultrasound guided nerve block: A randomised controlled trial
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Observe the PI ratio before and after interscalene block following 10ml, 15ml and 20ml of 0.5% bupivacaine.
研究概览
简要总结
Perfusion index (PI) is a new and objective way to evaluate the success of peripheral nerve block.[1] It can be used as an alternate means for sensory or motor function tests.
- Many studies have elucidated that PI changes in increments of double or even quadraple to signify successful block. Pardeep et al stated PI>3.2 and PI ratio of > 2.04 at 15min to be accurate predictors for block success in USG guided interscalene nerve blocks.[2] However many studies give contrasting results with respect to the cutoff values or the ratio of PI index.
- We hypothesize that the volume of LA used may be one of determining factor in the cutoff value of PI index for successful nerve block.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients of either sex aged between 18-60 years.
- •Scheduled for elective upper limb surgery (involving humerus or shoulder) under sole ultrasound guided interscalene block.
- •American society of Anesthesiologists physical status I or II.
排除标准
- •Patients with diabetes mellitus or peripheral vascular disease.
- •Allergy to local anaesthetics.
- •Local site infection
- •Refusal by patient for study.
- •Coagulopathy.
结局指标
主要结局
Observe the PI ratio before and after interscalene block following 10ml, 15ml and 20ml of 0.5% bupivacaine.
时间窗: Baseline and 15minutes
次要结局
- The cutoff values of PI and PI ratio as predictors of successful block(Baseline and 15 minutes)
研究者
Milon Vasant Mitragotri
KARNATAKA INSTITUTE OF MEDICAL SCIENCES