The Role of Umbilical Cord Serum Therapy on Improvement of Corneal Epithelial Defect Following Diabetic Vitrectomy
试验速览
- 阶段
- 1 期
- 试验地点
- 1
- 主要终点
- measurement of corneal epithelial defect
研究概览
简要总结
80 diabetic patients underwent vitrectomy and had no history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency will be randomized into two groups (double blind)to evaluate the role of umbilical cord serum therapy on improvement of corneal epithelial defect following diabetic vitrectomy. Both groups will take the conventional medication including Chloramphenicol, Betamethasone, Cycloplegic eye drops besides the case group will take umbilical cord serum eye drop in the eye operated. After surgery the corneal epithelial defect will be measured by slit lamp.
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diabetic patients with corneal epithelial defect following diabetic vitrectomy at labbafinejad Hospital
排除标准
- •Any history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency
- •Patients with one eye
- •Use of any eye drops except Chloramphenicol, Betamethasone, Cycloplegic and contact lens for corneal epithelial defect
研究组 & 干预措施
conventional therapy
chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours
干预措施: conventional therapy (Drug)
conventional therapy plus umbilical cord serum eye drop
干预措施: conventional therapy plus umbilical cord serum eye drop (Drug)
结局指标
主要结局
measurement of corneal epithelial defect
measurement of corneal epithelial defect in days 3,5,7,12 by slit lamp
次要结局
未报告次要终点