Impact of dietary supplement use of phytosterol on LDL cholesterol in children and adolescents

Not Applicable

• Conditions: hypercholesterolemia; E78.2; E78.4

• Registration Number: RBR-48yb5y
• Lead Sponsor: Hospital Universitário Pedro Ernesto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-02-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Children and adolescents between 6 and 19 years old with LDL-cholesterol above 110mg / d

Exclusion Criteria

Presence of heart disease, obesity, diabetes, nephrotic syndrome, systemic arterial hypertension, Down syndrome, Prader-Willi syndrome, hypothyroidism, Cushing's syndrome.

Children and adolescents using lipid-lowering foods or medications such as corticosteroids, estrogens, progesterone, beta-blockers, and thiazides.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Significant reduction of LDL-cholesterol by the lipidogram at the end of the eighth week of intervention in the experimental group, with a reduction of five per cent in the intervention group.;Reduction in fasting insulin values, verified by the laboratory dosage at the end of the eighth week of intervention in the experimental group, with reduction of five per cent.;Reduction of systolic and diastolic blood pressure values, measured by electronic device calibrated and validated for research at the end of the eighth week of intervention in the experimental group, with a five per cent reduction.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not expected