Sleep-related Breathing Disorders in Cardiological Outpatients From a German University Clinic - Prevalence, Classification, Diagnostic Accuracy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sleep Apnea Syndromes
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Prevalence of sleep-related breathing disorders
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of this study is to determine the prevalence of sleep-related breathing disorders (SRBD) in clinically stable cardiologic outpatients of a German university clinic by means of polygraphy.
Furthermore, the practicability of the underlying diagnostic process in clinical application is assessed as well as the sensitivity and specificity of polygraphy as compared to the reference standard of polysomnography. Another aim is to determine the individual cardiovascular risk profile by pulse wave analysis and risk classification according to European Society of Hypertension (ESH) and European Society of Cardiology (ESC), "ESH/ESC risk".
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥18 years
- •Present chronic cardiovascular disease (incl. but not limited to: ischemic heart disease, arterial hypertension, heart failure, atrial fibrillation)
- •Current clinically stable state (incl. patients after a cardiovascular-related, emergency hospital admission and subsequent recompensation towards the end of their hospital stay
Exclusion Criteria
- •Age \<18 years
- •Acute life-threatening disease (incl. but not limited to:instable angina pectoris, acute bronchial asthma, heart failure New York Heart Association (NYHA) stage IV, myocardial infarction, exacerbated chronic obstructive pulmonary disease (COPD), Malignant disease requiring treatment)
- •Pregnancy and/or lactation
- •Any medical, psychological or other condition impairing the patient's ability to provide informed consent
Outcomes
Primary Outcomes
Prevalence of sleep-related breathing disorders
Time Frame: Once within two days of inclusion
Prevalence of sleep-related breathing disorders as measured by ambulatory polygraphy and defined as an respiratory disturbance index of \>=15/h
Secondary Outcomes
- Number of patients included(through study completion, an average of 21 months)
- Number of patients with actually performed polygraphy(through study completion, an average of 21 months)
- Number of patients with assessable polygraphy(through study completion, an average of 21 months)
- Number of patients with actually performed polysomnography(through study completion, an average of 21 months)
- Number of patients with assessable polysomnography(through study completion, an average of 21 months)